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mcpB [2017-8-11 16:0:3]
membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein, receptor for asparagine
function
control of chemotaxis
product
methyl-accepting chemotaxis protein
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.1|Signal transduction in motility and chemotaxis] → [category|SW 4.1.1.1.4|Membrane-bound chemoreceptors][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
3,210,445 → 3,212,433
The protein
Paralogous protein(s)
[protein|F02E3080214A327E131ECDE0DBC52C57EFDFE2CE|McpA]Kinetic information
K(D) for asparagine: 14 myM [Pubmed|19864420]Modification
methylated at residues Gln371, Glu630, and Glu637 [Pubmed|20864474]Effectors of protein activity
asparagine (binds to the part of McpB that is exposed to the exterior) [Pubmed|19864420][SW|Localization]
cell membrane [Pubmed|18763711,21515776]localized at the cell poles, but in the presence of high asparagine concentration there is a reversible re-localization to the sides of the cell (lateral clusters) [Pubmed|21098025]Expression and Regulation
Operons
genes
[gene|E4E1020B799A1B403BDB4847B91B02D64D161AF3|mcpB]
description
[Pubmed|8188684]
sigma factors
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|8188684], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon]additional information
in minimal medium, McpB is present with 6,200 /- 1,900 molecules per cell [PubMed|21515776] view in new tabReferences
11722727,10825179,8251536,12909020,10196193,15544802,6137212,9194713,2505839,8188684,2105313,12123464,14731274,20864474,18763711,19864420,21098025,21515776,25039821,27899502